INVESTIGADORES
BUSI Maria Victoria
artículos
Título:
Drugs for the treatment of mitochondrial diseases.
Autor/es:
GOMEZ CASATI, D.F.; BUSI, M.V.
Revista:
Current Chemical Biology
Editorial:
BENTHAM SCIENCE PUBLISHERS
Referencias:
Año: 2019
ISSN:
2212-7968
Resumen:
Mitochondrial diseases are acomplex group of pathologies caused by mutations in genes coded in the nuclear and/or the mitochondrial DNA, which fulfilltheir function in the organelle. The diagnosis is also complex, since it depends on the integration of biochemical,histological and imaging data. There is not currently a fully effective treatment. However, it was demonstrated that the use of some vitamins, amino acids,antioxidants along with a proper diet and exercise have an important effectthat leads to improve the overall stateof patients with mitochondrial disorders. In this paper we review the use of some of these substances and theirefficacy in the treatment of these disorders.
