Effects of lack of pubertal, ovary-dependent programming on fructose induced dysmetabolism

VILLAGARCÍA HG; CASTRO MC,; MASSA ML; SPINEDI E; FRANCINI F

Congreso; XXV Congreso ALEH. 2018; 2018

Background: Bilateral ovariectomy (OVX)-induced Metabolic Syndrome in rats is characterized by increased body weight (BW)/fat and endocrine-metabolic dysfunctions. We currently evaluated the effect of lacking pubertal programming by endogenous peak of ovary-derived estradiol (E2), on endocrine-metabolic and liver functions when adulthood (90 days old) was reached.