INVESTIGADORES
DELPICCOLO Carina Maria Lujan
artículos
Título:
Solid-phase based synthesis of biologically promising triazolyl aminoacyl (peptidyl) penicillins
Autor/es:
CORNIER, P.G.; BOGGIAN, D. B.; MATA, E. G.; DELPICCOLO, C. M. L.
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2012 vol. 53 p. 632 - 636
ISSN:
0040-4039
Resumen:
An efficient and versatile methodology for the preparation of valuable triazolyl aminoacyl (peptidyl) penicillins is described. Solid-phase Cu(I)-catalyzed Hüisgen 1,3-dipolar cycloaddition was used as the key step showing general applicability and excellent regioselectivity either with CuI or [Cu(CH3CN)4]PF6 as Cu(I) source.
