Ghrelin signalling in the LHA of male mice induces orexin receptor 1 dependent activation of the NPY neurons in the ARH nucleus

BARRILE FRANCO, CASSANO DANIELA, GARCÍA ROMERO GUADALUPE, PERELLÓ MARIO

Buenos Aires

Congreso; XXXVII SAN 2022 Annual Meeting; 2022

Ghrelin is an stomach derived hormone that promotes a pletora of functionsincluding food consumption via the growth hormone secretagogue receptor(GHSR).- GHSR is mainly expressed in the brain, incluiding the lateral hypothalamic area(LHA) and the arcuate nucleus (ARH).orexin - LHA neurons are a key mediator of the ghrelin action on food intake.