Myelodysplastic Syndromes in South America: a Multi-national study of 1080 patients

BELLI, CAROLINA; FEITOSA PINHEIRO RONALD; BESTACH, YESICA; LARRIPA, IRENE; DA SILVA TANIZAWA, ROBERTA; ALFONSO, GRACIELA; GONZALEZ, JACQUELINE; ROSENHAIN, MARIANA; WATMAN, NORA; CAVALCANTE DE ANDRADE SILVA, MARCELA; NEGRI ARANGUREN, PEDRO; GARCÍA RIVELLO, HERNÁN; MAGALHAES, SILVIA; VALLADARES, XIMENA; UNDURRAGA, M SOLEDAD; RODRIGUES PEREIRA VELLOSO, ELVIRA

AMERICAN JOURNAL OF HEMATOLOGY

WILEY-LISS, DIV JOHN WILEY & SONS INC

Lugar: New York; Año: 2015 vol. 90 p. 851 - 858

0361-8609

There are previously reported data describing differences between Asian and European patients with Myelodysplastic Syndromes (MDS), few direct comparisons based on cancer registration characteristics or using cohorts to validate scoring systems. This is the first study from South-America which attempts to describe demographic, clinical features and outcome of MDS patients.We retrospectively analyzed 1080 patients with de novo MDS from Argentina (635), Brazil (345), and Chile (100). Chilean patients were younger (p=0.001) with female preponderance (p=0.071). Brazilian series showed a higher predominance of RARS subtype regarding FAB and WHO classifications (p