COMORBIDITY OF TYPE 2 DIABETES AND COVID-19 IN OLDER ADULTS

REPOSSI G; FERREYRA PISANI V; PRIOTTO S; LOPEZ CB; PIGINO BRUNO G; QUIROGA P; DIAZ-GEREVINI GT

Paris

Congreso; World Congress of Controversies in Obesity and Diabetes 2023; 2023

Controversies in Obesity and Diabetes Group

Older adults were the segment of the population most affected by the COVID19 pandemic. Type 2 diabetes (DBT2) also has a high prevalence in this agegroup, and its preexistence increases susceptibility, severity, and mortalityfrom COVID-19. The objectives of this work were to calculate and compare themain epidemiological variables, between groups with DBT2 and without DBT2in the study population, before and during the COVID-19 pandemic.Aim: To determine if there is an association of higher mortality from COVID-19with the presence of DBT2 in this population of older adults.Retrospective observational study (2018-2022) of medical records (n=1020) ofolder adults (≥65 years) treated at the "San Ricardo Pampuri" Center in VillaCarlos Paz, Córdoba, Argentina. They were statistically analyzed by ANOVAtest for quantitative data and Chi-square for categorical data using Infostat(α=0.05). The ethical norms of confidentiality and anonymity were respected. Population data: Gender distribution=62% male/38% female. 47% of thepopulation suffered from DBT2. Total COVID-19 prevalence: 46% of thepopulation (469 cases) during the study period. COVID-19 incidences: The incidences of COVID-19 were higher in the groupof diabetic patients during the 3 years of the study (see Table 1). COVID-19 mortality (%): Total Average=0.63; in Diabetic= 1.00 vs. NonDiabetic =0.32. 72% of the deceased had DBT2. Annual mortality andfatalities from COVID-19 were higher for those with DBT2. In 2020 and 2021COVID-19 was the leading cause of death in the population studied. COVID-19 lethality: The lethalies of COVID-19 were higher in the group ofdiabetic patients during the 3 years of the study (see Table 2). Excess Mortality: Average General Mortality (%) pre-pandemic (2018-2019)=1.86 vs pandemic (2020-2022)=2.72 (42.3% increment). 24 more peopledied than expected by this population. Average age of death from COVID-19: Diabetic =76.4 vs Non- Diabetic =84.1 Vaccination: 83% of deceased diabetic patients (2020-2022) were notvaccinated against SARS-COV-2. In 2022, coverage of more than 80% of thepopulation was achieved with vaccines (≥ 2 doses) against SARS-COV-2.Conclusion: the COVID-19 pandemic had a negative impact on the populationparameters studied, with these increases being greater in the group withDBT2. An increased mortality risk for COVID-19 was observed in patientswith T2DM. In 2022, there was a large decrease in incidence, mortality, andlethality (general and specific for COVID-19) compared to 2021. Theimprovement of the variables recorded in 2022 can be associated with thegreat coverage achieved in vaccination campaigns.