STUDY OF NEUROPROTECTIVE FACTORS MEDIATED BY OMEGA 3 AND COGNITIVE STIMULATION AGAINST AMNESIC MILD COGNITIVE IMPAIRMENT IN PATIENTS RESIDENTS OF THE CITY OF CÓRDOBA-ARGENTINA

CACERES MAGDALENA; BALASZCZUK, VERONICA; CASTRO ZAMPARELLA, TATIANA

Mar del Plata

Congreso; Reunión Anual de Sociedades de Biociencias 2022; 2022

General description: In older adults, neurodegenerative diseaseis very prevalent. In Latin American with low economic resources,public health proposals can be based on preventive and educationalactions, promoting brain protection factors. Background shows thata diet based on foods rich in essential fatty acids Omega 3 (ω3)contributes to the prevention of neurological clinical diseases. Goal:Explore neuroprotective factors mediated by dietary supplementation (ω3) and cognitive stimulation that could delay amnesic-typecognitive decline and thus, the diagnosis of dementia. Material andMethod: Non-probabilistic sample of adults between 60-80 yearsof age, both sexes, from Córdoba City, Argentina. N=14 divisionsin Healthy Control Group (S) and Cognitive Impairment (DC). Prepost evaluation neurocognitive battery and blood lipid profile weremade. Treatment with ω3 capsules (1 g) for 24 weeks and cognitivestimulation workshops for 24 weeks. To then exchange and complete 12 months with the other treatment. Results: The groups S:ω3and S:EC didn´t present changes pre-post treatment. In the DC:ω3group, maintenance of cognitive function is observed, as in theDC:EC group. Although the performance in the DC groups is lowerdue to the cognitive condition of the participants, no pre-post treatment changes are observed. The DC:ω3 and DC:EC groups arestatistically different from the S:ω3 group. Discussion and conclusions: In clinical practice, it is expected that an older adult with cognitive failures compatible with MCI get worse their performance fromone year to the next if the conditions and habits are not modified.The data obtained so far showed a tendency that the interventionsustained for 12 months at the level of external stimulation of cognitive functions and abilities and the adequate nutritional contributionprovided by ω3 sustains cognitive performance. Therefore, healthtrends are focused on prevention and thus provide quality of life tothe adult population.