INVESTIGADORES
LA VENIA Agustina
capítulos de libros
Título:
Peptidomimetics via Iminium Ion Chemistry on Solid Phase: Single, Fused, and Bridged Heterocycles
Autor/es:
AGUSTINA LA VENIA; PILAR VENTOSA-ANDRES; VIKTOR KRCHNAK
Libro:
Peptidomimetics II
Editorial:
Springer
Referencias:
Año: 2015; p. 105 - 126
Resumen:
Iminium ion chemistry represents a versatile transformation capable of introducing structurally diverse constraints into peptide backbones. The compatibility of iminium ion chemistry with traditional solid-phase peptide synthesis methods enables the introduction of constraints without requiring solution-phase synthesis. This chapter describes the introduction of constrained molecular scaffolds composed of single, fused, and bridged heterocycles into peptide backbones.
