INVESTIGADORES
LA VENIA Agustina
artículos
Título:
Biomimetic Domino Knoevenagel/Cycloisomerization Strategy for the Synthesis of Citridone A and Derivatives
Autor/es:
BHAT, AABID H.; QUIROGA, GASTÓN N.; LA-VENIA, AGUSTINA; GROVER, HUCK K.; RIVEIRA, MARTÍN J.
Revista:
JOURNAL OF ORGANIC CHEMISTRY
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2021
ISSN:
0022-3263
Resumen:
Studies on Knoevenagel condensations betweenconjugated dienals and 4-hydroxy-2-pyridone/quinolone-type 1,3-dicarbonylequivalents led to the development of a simple one-pot strategy to access citridoneA and related synthetic cyclopenta[b]furopyridones/quinolones.The present work highlights the power of domino cascades in the synthesis ofnatural product frameworks and may help promote future studies on thispromising new class of pyridone alkaloids.
