One-pot selective functionalization of polysaccharides with urea.

P. NORIEGA; V. GUNTERO; M. KNEETEMAN; M. PERALTA; C. FERRETTI

Chemistry Proceedings

MDPI

Lugar: Basel; Año: 2021 vol. 3 p. 1 - 5

2673-4583

Natural polysaccharides are polymers composed of monosaccharide units bound togetherby glycosidic linkages. In their native form, these polymers may not be able to provide all the desired properties for a particular application. Thus, the functionalization of their reactive hydroxylgroups would change their surface properties. In this work, we evaluated the derivatization of OHgroups of maltodextrin polysaccharide with urea. Through a one-pot selective procedure carriedout at room temperature for 3 h, urea united at maltodextrin through covalent bonding was obtained. The results show that after functionalization with urea, the pH and solubility in polar solvents of the new material increased. Derivatization of maltodextrin with urea confers stability, andterminal amide groups on the surface of this material represent a versatile reactive functional groupfor conjugation with other molecules for potential applications in the development of new materials.