URIC ACID LEVELS IN GESTATIONAL HYPERTENSIVE DISORDERS AND FETAL GROWTH RESTRICTION

ORTIZ, MARIA; BALCONI SILVIA; DAMIANO, ALICIA E; COROMINAS ANA; MASKIN BERNARDO

Ciudad Autonoma de Buenos Aires

Congreso; International Federation of Placenta Associations (IFPA) meeting 2019; 2019

International Federation of Placenta Associations

Objectives: To evaluate the levels of serum uric acid in pregnant womenwith fetal growth restriction associated or not with hypertensivedisorders.Methods: A retrospective descriptive-quantitative study was carried out inall women who attended their pregnancy at the Hospital Posadas during2014. Newborn of singleton pregnancies with fetal growth restriction(IUGR) and more than 22 weeks were studied. Uricemia ratio (uricemiaafter 20th week /uricemia before 20th week) was calculated in women whopresented IUGR associated or not to preeclampsia (PE) and gestationalhypertension (PIH).Results: In 3589 simple gestations analyzed, 100 presented PE (24 withIUGR), 208 PIH (19 with IUGR) and 3281 were normotensive (203 withIUGR).In the hypertensive group, the relative risk (RR) of having a newbornunder percentile 10 was 4.09(2.82-5.94) for PE and 1.72(1.12-2.64) for PIH.Regarding the evolution of pregnancy and birth, PE women have thehighest RR of prematurity, pathological Doppler, newborn weight