Undifferentiated pleomorphic sarcoma linked to Human T-cell Lymphotropic Virus type 1 in

BIGLIONE M; SANTINI ARAUJO E; BERINI C; LUPO S; CÁNEPA C

Congreso; III International Congress on Translational Medicine; 2016

Undifferentiated Pleomorphic Sarcoma (UPS) with giant cells is a very rare tumor especially in young adults. We report here a case of this type of tumor in a young woman infected by Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) who developed an HTLV-1 associated myelopathy associated to HTLV-1/Tropical Spastic Paraparesis (HAM/TSP) 3 years before. Reaching an accurate and timely diagnosis of UPS can be challenging due to lack of professional experience, difficulty in diagnosis/classification and delayed consultation. However, it is the key to changing the patient´s life expectancy significantly. That is the reason why the unapparent subclinical immunodeficiency state due to HTLV-1 retrovirus infection is a characteristic which deserves to be considered. Professionals should perform a close monitoring of HTLV-1 seropositive patients with HAM/TSP taking into account the possibility of developing any type of cancer.