INBIRS 24491
INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Impact of ART on the restoration of Th17 and Treg subpopulations in blood and genital mucosa during HIV infection
Autor/es:
JULIANA FALIVENE; M. PÍA HOLGADO; DIEGO ZURITA; NATALIA LAUFER; VALERIA FINK; CARINA CASTRO; MARIA PAULA CARUSO; LUCAS OJEDA; YANINA GHIGLIONE; M. JULIA RUIZ; PEDRO CAHN; OMAR SUED; GABRIELA TURK; M. MAGDALENA GHERARDI
Lugar:
Buenos Aires
Reunión:
Congreso; II French-Argentinan Immunology Meeting; 2015
Institución organizadora:
Sociedad Argentina de Inmunología
Resumen:
Th17 and Treg cells play a key role in HIV infection. Aim: to analyze the effect of antiretroviral therapy (ART) on these T-cell subsets in peripheral blood and female genital mucosa (FGM) in different patient groups.Groups: HIVneg (n=24); HIV+ART+ (>5 years on ART, n=11); HIV+ARTnaïve (n=15). Samples: Peripheral blood: PBMCs; FGM: Cervical mononuclear cells (CMCs).PBMCs: %Th17 in HIV+ART+ was higher vs HIV+ARTnaive (p
