INVESTIGADORES
TEKIEL Valeria Sonia
artículos
Título:
Gene discovery in Triatoma infestans
Autor/es:
AVILA, ML; TEKIEL, V; MORETTI, G; NICOSIA, S; BUA, J; LAMMEL, EL; STROPPA, MM; GEREZ DE BURGOS, N; SÁNCHEZ, DO
Revista:
PARASITES AND VECTORS
Editorial:
BIOMED CENTRAL LTD
Referencias:
Año: 2011 vol. 4 p. 39 - 45
ISSN:
1756-3305
Resumen:
Abstract
Background:
Triatoma infestans is the most relevant vector of Chagas disease in
the southern cone of South America. Since its genome has not yet been
studied, sequencing of Expressed Sequence Tags (ESTs) is one of the
most powerful tools for efficiently identifying large numbers of
expressed genes in this insect vector.
Results:
In this work, we generated 826 ESTs, resulting in an increase of 47%
in the number of ESTs available for T. infestans. These ESTs were
assembled in 471 unique sequences, 151 of which represent 136 new genes
for the Reduviidae family.
Conclusions:
Among the putative new genes for the Reduviidae family, we
identified and described an interesting subset of genes involved in
development and reproduction, which constitute potential targets for
insecticide development.