INVESTIGADORES
GOMEZ Sonia Alejandra
artículos
Título:
apid identification of OXA-48 and OXA-163 subfamily in carbapenem resistant gram-negative bacilli with a novel immunochromatographic lateral flow assay.
Autor/es:
F PASTERÁN; DENORME L; OTE, I; GOMEZ SA; DENISE DE BELDER; GLUPCZYNSKI Y; BOGAERTS P; GHIGLIONE B; POWER P; MERTENS P; A. CORSO
Revista:
JOURNAL OF CLINICAL INVESTIGATION
Editorial:
AMER SOC CLINICAL INVESTIGATION INC
Referencias:
Lugar: Washington; Año: 2016
ISSN:
0021-9738
Resumen:
We assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allows rapid (less than 4 minutes) and reliable direct confirmation of OXA-163/48-like enzymes (100% sensitivity and specificity) from culture colonies recovered from both, solid media and spiked blood culture bottles.