INVESTIGADORES
GOMEZ Sonia Alejandra
artículos
Título:
Rapid Identification of OXA-48 and OXA-163 Subfamilies in Carbapenem-Resistant Gram-Negative Bacilli with a Novel Immunochromatographic Lateral Flow Assay
Autor/es:
F PASTERÁN; LAURENCE DENORME; ISABELLE OTE; GÓMEZ, SONIA ALEJANDRA; DE BELDER D; YOURI GLUPCZYNSKI; PIERRE BOGAERTS; BARBARA GHIGLIONE; POWER P; PASCAL MERTENS; A. CORSO
Revista:
JOURNAL OF CLINICAL INVESTIGATION
Editorial:
AMER SOC CLINICAL INVESTIGATION INC
Referencias:
Lugar: Ann Arbor, Michigan; Año: 2016 vol. 54 p. 2832 - 2836
ISSN:
0021-9738
Resumen:
We assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allowed rapid (less than 4 min) and reliable direct confirmation of OXA-163- and/or OXA-48-like enzymes (with 100% sensitivity and 100% specificity) from cultured colonies that were recovered from both solid medium and spiked blood culture bottles.
