INVESTIGADORES
GÜERCI Alba Mabel
artículos
Título:
Assessment of Genotoxic Damage in Lymphocytes of Hospital Workers Exposed to Ionizing Radiation in Argentina
Autor/es:
ALBA M. GÜERCI, PHD; CLAUDIA A. GRILLO, PHD; FERNANDO N. DULOUT, ME; ANALÍA I. SEOANE, PHD
Revista:
Archives of Environmental & Occupational Health,
Referencias:
Año: 2007 vol. 61 p. 163 - 169
Resumen:
The authors aimed to assess genotoxic damage in the lymphocytes of workers chronically
exposed to ionizing radiation. The studied population included 15 exposed donors of the radiology
unit of a public hospital in La Plata, Argentina. The control group included 15 nonexposed
employers from administrative areas that the authors matched by age, sex, and smoking habits. The
mean frequency of cytogenetic damage was higher in the exposed group than in the unexposed
group for aneuploidy and structural chromosome aberrations. They observed the highest difference
when achromatic lesions (or gaps) were considered. The comet assay showed that the frequency of
cells with low damage was higher in the exposed group than in the unexposed group. A mean length
analysis showed significant differences between exposed and nonexposed people. The results can be
considered to be consistent evidence of occupational radiation exposure, and the results indicate that
the workers must be advised to avoid or minimize their exposure.The authors aimed to assess genotoxic damage in the lymphocytes of workers chronically
exposed to ionizing radiation. The studied population included 15 exposed donors of the radiology
unit of a public hospital in La Plata, Argentina. The control group included 15 nonexposed
employers from administrative areas that the authors matched by age, sex, and smoking habits. The
mean frequency of cytogenetic damage was higher in the exposed group than in the unexposed
group for aneuploidy and structural chromosome aberrations. They observed the highest difference
when achromatic lesions (or gaps) were considered. The comet assay showed that the frequency of
cells with low damage was higher in the exposed group than in the unexposed group. A mean length
analysis showed significant differences between exposed and nonexposed people. The results can be
considered to be consistent evidence of occupational radiation exposure, and the results indicate that
the workers must be advised to avoid or minimize their exposure.