INVESTIGADORES
GAVERNET Luciana
artículos
Título:
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV
Autor/es:
GAVERNET LUCIANA; GONZALEZ FUNES JOSE LUIS; PALESTRO PABLO; BRUNO BLANCH LUIS E.; ESTIU GUILLERMINA; MARESCA ALFONSO; BARRIOS IVANA A.; SUPURAN CLAUDIU
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY.
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2013 p. 1410 - 1418
ISSN:
0968-0896
Resumen:
A set of sulfamides and sulfamates were synthesized and tested against several isoforms of carbonic anhydrase: CA I, CA II, CA VII, CA XII and CA XIV. The biological assays showed a broad range of inhibitory activity, and interesting results were found for several compounds in terms of activity (Ki
