INVESTIGADORES
GAVERNET Luciana
artículos
Título:
Docking applied to the study of inhibitors of c-Met kinase
Autor/es:
GAVERNET LUCIANA; PALESTRO PABLO; BRUNO-BLANCH LUIS E.
Revista:
ISRN Physical Chemistry
Editorial:
ISRN
Referencias:
Año: 2012 p. 1 - 5
ISSN:
2090-7761
Resumen:
Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this investigation we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported.
