CONICET | Buscador de Institutos y Recursos Humanos

Purpose : The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280 ? 100 nm) radiation in Drosophila melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. to UV-C (ultraviolet C, 280 ? 100 nm) radiation in Drosophila melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. to UV-C (ultraviolet C, 280 ? 100 nm) radiation in Drosophila melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280 ? 100 nm) radiation in Drosophila melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Drosophila melanogaster , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. , implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Materials and methods : We performed a QTL scan inWe performed a QTL scan in D. melanogaster recombinant inbred lines (RIL) constructed from parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. recombinant inbred lines (RIL) constructed from parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. Results : Signifi cant QTL were detected on all three major chromosomes. Among these, multiple trait composite interval mapping revealed a signifi cant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. chromosomes. Among these, multiple trait composite interval mapping revealed a signifi cant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. chromosomes. Among these, multiple trait composite interval mapping revealed a signifi cant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. Signifi cant QTL were detected on all three major chromosomes. Among these, multiple trait composite interval mapping revealed a signifi cant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. Conclusions : This study shows substantial genetic variation for UV-C radiation resistance in D. melanogaster , with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. for UV-C radiation resistance in D. melanogaster , with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. for UV-C radiation resistance in D. melanogaster , with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. This study shows substantial genetic variation for UV-C radiation resistance in D. melanogaster , with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. D. melanogaster , with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals.