MicroRNAs in parasitic tapeworms: discovery, functional analysis and potential role in host-parasite communication

BREHM K; MALDONADO L; MACCHIAROLI N ; CUCHER M; KAMENETZKY L; PÉREZ M; ROSENZVIT M C; MARCILLA A; ANCAROLA M E

Cope Cod, MA, USA

Congreso; Molecular Helminthology: An Integrated Approach; 2017

Tapeworms (Cestoda) are etiological agents of neglected diseases such as echinococcosis and neurocysticercosis. MicroRNAs (miRNAs) are small silencing RNAs with key roles in multiple cellular processes. We identified miRNAs in cestodes for the first time and reported differential expression among developmental stages. The objectives of this work are to compare miRNA repertoire and expression profile among tapeworms and to start addressing their functions.