IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
FOLIC ACID ENCAPSULATION IN A CARBOXYMETHYL CELLULOSE MATRIX: EVALUATION OF ITS BIOAVAILABILITY USING THE CELLULAR MODEL Caco-2
Autor/es:
MARTÍNEZ, JIMENA H.; OSCAR E PÉREZ; MARCOS PALAVECINO; FLORENCIA TARSIA
Lugar:
Buenos Aires
Reunión:
Congreso; Reunión Conjunta de Sociedades de Biociencias 2017; 2017
Institución organizadora:
Sociedad Argentina de Investigación Clínica
Resumen:
Folic Acid (FA) is a vitamin particularly sensitive to the acidic pH of the stomach and this leads to a low bioavailability in the small intestine epithelium. Due this, new approaches for improving FA bioavailability and stability are required. In this study we proposed that FA can be encapsulated into a carboxymethyl cellulose matrix (CMC). This strategy could allow a controlled release of FA in the small intestine cells.
