Clinical characteristics and prognostic factors of patients with febrile neutropenia

PARODI, ROBERTO L.; LAGRUTTA, MARIANA; GENESIO A; GROSSELLI W; RAMALLO M; MARTIN M; MORENO J; SOMMER L; GRECA A; BOTTASSO O

Mar del Plata

Congreso; LXVII Reunión Anual de la SAIC, 16-19 noviembre de 2022; 2022

Sociedad Argentina de Investigación Clínica

Our study investigated the clinical and epidemiological features of febrile neutropenia episodes at a high-complexity hospital in Rosario city, in addition to ascertaining biochemical variables (erythrocyte sedimentation rate -ESR-), C reactive protein -CRP-, red blood cell distribution width -RDW-). Some relationships between such variables with disease outcomes may eventually contribute to better patient management. We conducted a descriptive, analytical, observational, prospective study of consecutive inpatients with febrile neutropenia (March 2016-March 2020) who were followed up during such complications. Sixty-one episodes of febrile neutropenia were recorded; 28 women/33 men, with a median age of 40 years; 36 of them following antineoplastic chemotherapy. There were 9 deaths. Blood cultures were positive in 19.6% of episodes (12 positive cultures). Statistical analysis (univariate and adjusted methods) showed an association between mortality, lower ESR values (p