Green transesterification of

G. SATHICQ; L. MUSANTE; G. ROMANELLI; G. PASQUALE; J. AUTINO; H. THOMAS; P. VÁZQUEZ

Texas

Conferencia; 20th North American Meeting of the Catalysis Society; 2007

Transesterification reaction is a useful tool in organic synthesis, having wideapplication both in academic as well as industrial research; for example, in the preparation of--ketoesters used as chemical intermediates in pharmaceutical, agrochemical, chemical andpolymer industry. A non-catalytic transesterification of --ketoesters requires the use of eitherexcess of --ketoesters or longer reaction time; and employs high boiling alcohols. In addition,this reaction is currently catalyzed by strong acids such as hydrochloric, sulphuric and ptoluenesulphonic.In this paper, we focused on further effect of the catalytic activity of hybridmaterials based on silica sol-gel; we report here a mild and sustainable transesterification of --ketoesters with various alcohols (Scheme 1).Scheme 1. Transesterification reaction: General Scheme