: Synthetic and semi-synthetic polymers for pharmaceutical Applications.

MACCHIONE, MICAELA; ARISTIZABAL DARIANA; FIGUEROA FRANCISCO; STRUMIA MIRIAM

Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies

Academic Press

Año: 2021; p. 45 - 70

This chapter provides a general description of the most common synthetic and semi-synthetic polymers, ranging from macro to nanoscopic sizes that have been used in the preparation of different pharmaceutical dosage. The polymers represent an important component of several pharmaceutical formulations. It is well-known that the formulation and clinical performance of pharmaceutical dosage forms depend on the physicochemical properties of the polymers used. Therefore, the impact of polymers is a consequence of the great advances in chemical synthesis and in the analysis of their properties. In the different sections of this chapter, the most used synthetic methodologies for obtaining synthetic and semi-synthetic polymers with some representative examples of their pharmaceutical applications will be presented.