Copper stress targets the Rcs system to induce the multiaggregative behavior in a copper-sensitive Salmonella strain

LUCAS B. PONTEL; ALEJANDRO PEZZA; FERNANDO C. SONCINI

JOURNAL OF BACTERIOLOGY

AMER SOC MICROBIOLOGY

Lugar: Washington; Año: 2010 vol. 192 p. 6287 - 6290

0021-9193

Salmonella delta-cuiD strains form mucoid colonies on copper-containing solid media. We show here that this multiaggregative behavior is caused by the Rcs-dependent induction of colanic acid extracellular polysaccharide. Deletion of cps operon genes in a delta-cuiD strain increased the sensitivity to copper, indicating a role for colanic acid in copper resistance.