Dynamics of the Antibody - T.cruzi Competition during Chagas Infection: Prognostic Relevance of Intracelular Replication.

G. J. SIBONA; C. A. CONDAT; S. COSSY ISASI

PHYSICAL REVIEW E - STATISTICAL PHYSICS, PLASMAS, FLUIDS AND RELATED INTERDISCIPLINARY TOPICS

Año: 2005 vol. 71 p. 20901 - 20904

1063-651X

A recently proposed model for the competitive parasite-antibody interactions in Chagas disease is extended by separately describing the parasitic intracellular and extracellular phases. The model solutions faithfully reproduce available population data and yield predictions for parasite-induced cardiac cell damage.