INVESTIGADORES
SCHILARDI Patricia Laura
congresos y reuniones científicas
Título:
Nanomechanical characterization of biointerfaces by Peak Force QNM®
Autor/es:
CAROLINA DIAZ; ALEJANDRO MIÑAN; DIEGO E. PISSINIS; PATRICIA L. SCHILARDI; LÍA I. PIETRASANTA
Lugar:
Carlos Paz, Córdoba
Reunión:
Congreso; XLII Reunión Anual de la Sociedad Argentina de Biofísica; 2013
Institución organizadora:
Sociedad Argentina de Biofísica
Resumen:
The design, development and characterization of substrates with different physical, chemical and mechanical properties are critical for the study of biologically active surfaces and biointerfaces1. These kinds of devices involve the interaction of synthetic materials with biological systems and require a complete understanding of the physical properties of molecules, composites and nanostructures. Since its development, AFM is a powerful diagnostic and investigation tool. Nowadays, Peak Force QNM® 2 allows quantitative nanomechanical mapping of material properties, including modulus, adhesion and dissipation, while simultaneously imaging sample topography at high resolution. In order to study cellular mechanostransduction, we characterize interfacial arquitectures and micro-nano structured platforms based on molecular recognition.