Spontaneous adsorption of silver nanoparticles on Ti/TiO2 surfaces Antibacterial effect on Pseudomonas aeruginosa.

CONSTANZA Y. FLORES; CAROLINA DIAZ; ALDO RUBERT; GUILLERMO BENÍTEZ; M. S. MORENO; MONICA FERNANDEZ LORENZO DE MELE; ROBERTO C. SALVAREZZA.; PATRICIA L. SCHILARDI; CAROLINA VERICAT

Workshop; Eulasur School and Workshop on “Properties and Applications of Nanomaterials; 2010

Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial colonization that could lead to infection, inflammation,and finally to implant failure. Silver nanoparticles (AgNPs) have demonstrated an excellent performance as biocides, and thus their integration to titanium surfaces is an attractive strategy to decrease the risk ofimplant failure. In this work a simple and efficient method is described to modify Ti/TiO2 surfaces with citrate-capped AgNPs. These nanoparticles spontaneously adsorb on Ti/TiO2, forming nanometer-sized aggregates consisting of individual AgNPs that homogeneously cover the surface. The modified AgNP–Ti/TiO2 surface exhibits a good resistance to colonization by Pseudomonas aeruginosa, a model systemfor biofilm formation.