Correlationbetweenfunctional and ultrastructuralsubstrate In BrugadaSyndrome.

TAUBER P.E.; SANCHEZ, SARA SERAFINA DEL V.

HeartRhythm Case Reports

Elsevier

Año: 2015 vol. 3 p. 211 - 216

2214-0271

Brugada syndrome (BS) was reported for the first time in 1992 and is associated with an ST-segment elevation in the right precordial leads in the absence of any demonstrable structural heart disease, as well as with sudden cardiac death due to ventricular fibrillation (VF).1 A patent type 1 electrocardiogram (ECG) is diagnostic of BS and is characterized by a coved ST-segment elevation of Z2 mm followed by a negative T wave in 41 right precordial lead (V1 to V3) in the presence or absence of a sodium channel?blocking agent, and in conjunction with 1 of the following: documented VF, polymorphic ventricular tachycardia (VT), a family history of sudden cardiac death at o45 years of age, coved-type ECGs in family members, inducibility of VT/VF with programmed electrical stimulation, syncope, or nocturnal agonal respiration.