INVESTIGADORES
MOTRAN Claudia Cristina
artículos
Título:
Helminths Turning on the NLRP3 Inflammasome: Pros and Cons
Autor/es:
CELIAS, DAIANA PAMELA; MOTRÁN, CLAUDIA CRISTINA; CERVI, LAURA
Revista:
TRENDS IN PARASITOLOGY
Editorial:
ELSEVIER SCI LTD
Referencias:
Año: 2020 vol. 36 p. 87 - 90
ISSN:
1471-4922
Resumen:
Helminth infections can activate multimeric protein complexes called inflammasomes. In this forum we summarize the main effects of the NLRP3 inflammasome activation, including control of excessive Th2 response and immunopathology induction. These mechanisms would ensure the survival of both the host and the parasite.