INVESTIGADORES
MARTIN Gabriela Adriana
artículos
Título:
43. Histamine regulates the expression of histidine decarboxylase in NMU-induced tumors in rats.
Autor/es:
N. ENGEL, G. CRICCO, C. DAVIO, G. MARTIN, M. CROCI, C.FITZSIMONS, R. BERGOC AND E. RIVERA
Revista:
INFLAMMATION RESEARCH
Editorial:
BIRKHAUSER VERLAG AG
Referencias:
Lugar: BASEL; Año: 1996 vol. 46
ISSN:
1023-3830
Resumen:
In a chemically induced model of mammary tumors, wehave previously reported that histamine regulates tumorgrowth by acting through specific H1 and H2 membranereceptors and that high levels of endogenouslysynthesized histamine behave as an autocrine growthfactor . On the basis of these data, we investigated thein vivo action of fluoromethyl-histidine (MFMH), aspecific histidine decarboxylase (HDC) inhibitor, andwhether histamine regulated HDC levels via its membrane receptors.
