Investigation On Pd/SeO2/SiO2 For α-Pinene Oxidation. Characterization by Transmission Electron Microscopy (TEM)

VOLPE, M.A.; FARAONI, M.B.; MUSSO, F.; YAÑEZ, M.J.

MICROSCOPY & MICROANALYSIS

CAMBRIDGE UNIV PRESS

Año: 2020 vol. 26 p. 83 - 84

1431-9276

Myrtenal (3) has received a growing interest in research for its bioactive properties, and it wasdiscovered that it exhibits a broad spectrum of biological activities [1, 2]. Allylic oxidation withselenium oxide (SeO2) is one of the most used techniques in the traditional methodology, but it hasseveral disadvantages, such as the use of high stoichiometric ratios, product mixes, very long reactiontimes and generation of colloidal selenium species that are difficult to eliminate, these being very toxicto the environment [3]. The heterogenization of oxidation reactions traditionally carried out followingclassical organic synthesis methodology presents a high impact in the context of the Green Chemistryprinciples.In line with this, there are several reports regarding α-pinene (1) as a starting compound, molecularoxygen as oxidizing agent and catalysts based on supported metals, such as Pd, Pt, Fe, Ru and, Cr.However, this allylic oxidation produces verbenol (4), verbenone (5) and α-pinene epoxide (6), withoutthe production or the desired myrtenal (Figure 1) [4 ? 6].