INVESTIGADORES
FURLAN Ricardo Luis Eugenio
artículos
Título:
Dynamic Combinatorial Chemistry
Autor/es:
OTTO, S; FURLAN, RLE; SANDERS, JKM
Revista:
DRUG DISCOVERY TODAY
Editorial:
Elsevier Science Ltd
Referencias:
Lugar: Oxford; Año: 2002 vol. 7 p. 117 - 125
ISSN:
1359-6446
Resumen:
A combinatorial library that responds to its target by increasing the concentration of their strong binders at expenses of weak binders sounds ideal. Dynamic combinatorial chemistry has the potential to achieve exactly this. In this review, we will highlight the unique features that distinguish dynamic combinatorial chemistry from traditional combinatorial chemistry, and that could make a useful addition to the set of combinatorial techniques used in drug discovery.
