Comparative hydrothermal synthesis of hydroxyapatite by using cetyltrimethylammonium bromide and hexamethylenetetramine as additives

HERNÁNDEZ ORTIZ, GLORIA M.; PARRA, RODRIGO; FANOVICH, MARÍA A.

CERAMICS INTERNATIONAL

ELSEVIER SCI LTD

Año: 2018 vol. 44 p. 3658 - 3663

0272-8842

Comparative synthesis ways for preparing HA (Ca10(PO4)6(OH)2)nanoparticles in presence of hexamethylenetetramine (HMTA) andcetyltrimethylammonium bromide (CTAB) were carried out. The reactionswere performed in a Teflon-lined stainless-steel reactor at 120ºC during12 h. The effects of the additive concentration and the cooling mode(fast and slow) were analyzed. The obtained powders were characterized byX-ray Diffraction (XRD), Raman Spectroscopy, Dynamic Light Scattering(DLS) and Scanning Electron Microscopy (SEM). The two hydrothermal wayscarried out for preparing HA nano powders produced a pure crystallinephase of HA. When the fast cooling mode was used, the obtained particlesexhibited smaller mean particle sizes. The highest concentrations of usedadditives (HTMA or CTAB) resulted in opposite effect on the obtained meanparticle size of HA particles. These observations were associated to thedifferent behaviors of this additives in the HA formation processes.