In a low-income Argentinean cohort of pregnant women , perceived maternal stress during pregnancy alters some aspects of newborn development

BROCCO MARCELA ADRIANA; GONZÁLEZ MA. AURELIA; FRASCH, MARTIN G.; RUMI, MERCEDES; SUSACASA, SANDRA; ANTONELLI, MARTA C

Congreso; IFPA 2019; 2019

Objective: Prenatalstress (PS) during pregnancy affects in uterus and postnatal child braindevelopment. Key systems affected are the hypothalamic-pituitary-adrenal axisand the autonomic nervous system.Methods:Prospective case-controlstudy matched for maternal age, parity and gestational age from 28 weeksto term was carried out at Hospital Materno Infantil Ramón Sarda (CEI Protocol 09/2015).Using the Cohen Perceived Stress Scale (PSS) questionnaire, pregnant women withPSS-10 ≥ 19 were classified as stress group (SG). Women withPSS-10 < 19 served as control group (CG). Maternal hair cortisol wasmeasured 24-48 h after delivery. Clinical data from mothers and newborns wasrecorded. One month after birth, children were evaluated with Bayley´s scaleand mothers with the Edinburgh Post-partum Depression Scale (EPDS).Results: For a pilotstudy, 50 women were interviewed, 37/50 had a PSS-10