INVESTIGADORES
APPIGNANESI Gustavo Adrian
artículos
Título:
Semiempirical prediction of protein folds
Autor/es:
A. FERNÁNDEZ; A. COLUBRI; G. A. APPIGNANESI
Revista:
PHYSICAL REVIEW E - STATISTICAL PHYSICS, PLASMAS, FLUIDS AND RELATED INTERDISCIPLINARY TOPICS
Editorial:
American Physical Society
Referencias:
Año: 2001 vol. 64 p. 219011 - 2190114
ISSN:
1063-651X
Resumen:
A semiempirical approach to predict expeditious pathways and native backbone geometries of proteins that fold under renaturation conditions was discussed. A combinatorial procedure was also introduced to evaluate coarsely defined torsional states of the chain and translate them into meaningful patterns of long-range interactions. The structure prediction based on the local contributions to the potential energy was also presented using the predictive power of the algorithms.
