INVESTIGADORES
ALMIRON Walter Ricardo
congresos y reuniones científicas
Título:
Ecoepidemiología de Flavivirus, monitoreo de sus vectores (Diptera: Culicidae) y reservorios en Pampa del Indio, provincia de Chaco, Argentina
Autor/es:
STEIN, M.; ORIA, GRISELDA; DIAZ A.; ALMIRÓN, W. R.
Lugar:
Buenos Aires
Reunión:
Otro; Anales de la Fundación Alberto Roemmers; 2014
Institución organizadora:
Fundación Alberto Roemmers
Resumen:
To survey and identify activity of Flavivirus, mosquitoes (Culicidae) and monkeys (Alouata caraya) were captured, between december 2009 and december 2011, in Pampa del Indio, province of Chaco. With the same objective human sera were obtained from patients who attended to hospital of Pampa del Indio city.Seroprevalence studies for St. Louis encephalitis viruses (SLEV) and WestNile viruses (WNV) were conducted in humans and monkeys. Also a total of 1949mosquitoes (98 pools) belonging to 18 species were analyzed for Flavivirusdetection. Ten pools were positive for Flavivirus: 5 Culex spp., 1 Cx. bidens,1 Mansonia spp., 1 Ochlerotatus stigmaticus, 1 Oc. scapularis and 1 Psorophoraspp. Five pools were analyzed by RT-Nested PCR technique specific to SLEV,resulting positive two of them (Ps. spp., and Oc. stigmaticus). Since this isthe first report of infection for Cx. bidens and Oc. stigmaticus in Argentina.None of the monkeys sera were positive for flavivirus. A total of 124 humansera were analyzed by NTab by plaque reduction neutralization test, usingVero cells. Twenty eight were positive: 40% for SLEV 6 and 4.8% for WNV. Two individuals had antibodies to both viruses (SLEV and WNV). This could be due to sequential infection or serologic crossings, more than one flavivirus circulating in this study area. These results contribute to the knowledge of the activity of these viruses in the province of Chaco and alert about the necessary implementation of monitoring programs for these viruses. Differential diagnosis should also be considered, because these arboviruses have similarity in clinical presentation and antigenic characteristics, in order to make possible earlydetection of febrile disease outbreaks and assess their impact on publichealth.