INTEQUI 20941
INSTITUTO DE INVESTIGACIONES EN TECNOLOGIA QUIMICA
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A SEMI-SYNTHETIC MOLECULE DERIVED FROM DEHYDROLEUCODINE AFFECTS THE TRYPANOSOMA CRUZI CELL CYCLE
Autor/es:
GUARISE, C.; BARRERA, P.A.; CIFUENTE, DIEGO A.; GOMEZ, J.; SOSA, M.A.
Reunión:
Congreso; XXXVII Reunión Científica Anual de la Sociedad de Biología de Cuyo; 2019
Resumen:
Trypanosoma cruzi is a parasite causing of Chagas disease which is endemic in Latin America, but in the last 20 years it has expanded worldwide. The sesquiterpene lactones (STLs) are natural compounds purified from native plants of Argentina with multiple pharmacological applications. This study is focused on elucidating the action mechanisms of DhL and its derivative DC-X11, obtained by chemical substitution, on T. cruzi epimastigotes (strain Dm28c).
