23. Computational study of the interaction between beta-lactoglobulin and polyelectrolytes

EVELINA QUIROGA; CLAUDIO NARAMBUENA; BOJANICH, LUCIANO; ANTONIO JOSÉ RAMIREZ-PASTOR; TORRES, PAOLA; BOERIS, VALERIA; FABRICIO SANCHEZ-VARRETTI

Sao Paulo

Workshop; Workshop School on Biological Soft matter from molecular interactions to engineered materials; 2017

ICTP-SAIFR/IFT-UNESP

β-lactoglobulin (BLG) is the main protein in the lacteum serum. The aim of this work is the purification of BLG throughtout a simple, fast and economic method that can be applied at an industrial scale using polyelectrolytes (PE). Polyssacharides act as polyelectrolytes which have the capacity to coacervate proteins. The electrostatic interaction plays a key role, it depends on the pH conditions and salt concentration.In this work we study through Monte Carlo simulation the interactions BLG-polyanion and BLG-polycation as a funtion of pH.