EFFECTS OF CADMIUM EXPOSURE IN SERUM PARAMETERS AND AORTA MORPHOLOGY

QUIROGA LOHAIZA CLAUDIO DARIO; ALVAREZ SILVINA M; PIGUILLEM SILVANA; VALDEZ SUSANA R; ALVAREZ OLMEDO DG; BIAGGIO V; GIMENEZ MARIA S

ESTANCIA GRANDE, SAN LUIS

Congreso; REUNION ANUAL SOCIEDAD DE BIOLOGIA DE CUYO; 2014

SOCIEDAD DE BIOLOGIA DE CUYO

Cadmium (Cd) is a toxic metal and an important environmental contaminant. The goal of this work was to study the effect of chronic exposure to Cadmium in different serum parameters and the histoarchitecture of rat aorta. Male Wistar rats (21 days of age) were divided into two groups: the exposed group (Cd) which received 15ppm of Cd as CdCl2 in drinking water ad libitum for 8 weeks and the control group (Co) which received water without Cd. The rats were killed and aortas and serum were obtained. We measured serum triglycerides, cholesterol and uric acid by spectrophotometric methods.Aortas were fixed, sectioned, stained, and examined for evidence of injury. Serum Triglycerides showed a significant increase in Cd (p