PHYTOESTROGENIC ACTIVITY OF Prosopis torquata (en prensa)

MARIA BEATRIZ NUÑEZ; ANTONIO MARCELO MANGIONE; SALINAS ADRIANA; CARRASCO MIRTA; GIL ESTEBAN; AGUILERA-MERLO, CLAUDIA

MAIPU

Jornada; XXX Sociedad de Biología de Cuyo; 2013

SOCIEDAD DE BIOLOGIA DE CUYO

PHYTOESTROGENIC ACTIVITY OF Prosopis torquata Nuñez MB1, Mangione AM1,2, Salinas A1, Carrasco M1, Gil E1 y Aguilera Merlo C1. 1 Departamento de Bioquímica y Ciencias Biológicas. Facultad de Química, Bioquímica y Farmacia. UNSL. 2 IMIBIO CCT San Luis. E-mail: betinunezi@gmail.com Many studies mention the fruit consumption by wild canids. One of this vegetal species is Prosopis torquata. Prosopis? species have phytoestrogens, which are compounds with hormonal functions and may have different results both females and males. The question arises if the consumption of these fruits could be regulating the reproductive cycle in wild species, for example Lycalopex griseus. It was used as a model prepubertal female Wistar rats. The variables measured as indicators of estrogenic activity were: vaginal opening time (OV), macroscopic evaluation of the reproductive organs (edema and tissue turgor) and microscopic examination of the ovaries. The results of the AV time, didn´t show differences between diets with fruits P. torquata and the control. The morphological variations in the ovary, oviduct and uterus between batches, were remarkable, showing a marked irrigation in the uterus of females who consumed fruits. With regard to the histological analyzes in the rats? ovaries that consumed fruits, phytoestrogens? action is seen due to the high number of follicles at different stages, corpus luteum?s absence and the presence of cells with apoptotic features. According to what has been analyzed so far, the possibility cannot be excluded that the ingestion of vegetal material in wild mammals, is a reproduction?s regulator.