Gender Differences in Physical, Chemical and Metabolic Factors Involved in Nephrolithiasis.

MOYANO MARIO FRANCO; FUENTES LUCIA; GUILLERMO OSVALDO ORELLANO

San Luis, Villa de Merlo

Congreso; XXXV Reunión Científica Anual de la SBCuyo; 2017

Sociedad de Biologia de Cuyo

Kidney stones forming require investigations to detect predisposing metabolic abnormalities. A variety of dietary and metabolic factors may contribute or cause stone formation in nephrolithiasis. Some metabolic causes are hypercalciuria, hypocitraturia, gout, hyperoxaluria, and hyperuricosuria. The aim was to investigate physical, chemical and metabolic abnormalities involved in the risk of lithogenesis in both sex. Observational and cross-sectional retrospective study was undertaken. Total metabolic variables were assessed in the data base, including serum and urine chemistries. 421 patients (20-70 years), 57.5% women (W) and 42.5% men (M), Age (years): 44.6 ± 13.8(W) 43.9 ± 13.9 (M), weight (Kg): 64.4 ± 13.1(W) 85.5 ± 14.5 (M), p< 0.0001. BMI: 24.9 ± 4.7(W) 28.2 ± 4.3 (M), p< 0.0001. Serum uric acid, creatinine, urea (mg/dl) increased significantly in M (p