IMBECU   20882
INSTITUTO DE MEDICINA Y BIOLOGIA EXPERIMENTAL DE CUYO
Unidad Ejecutora - UE
capítulos de libros
Título:
Expression of Inflammatory Molecules in an Experimental Vascular Remodeling Model
Autor/es:
RENNA NF; MIATELLO RM
Libro:
Insulin Resistance: New Research
Editorial:
Novasiences
Referencias:
Lugar: New York; Año: 2009; p. 130 - 152
Resumen:
Vascular diseases, including atherosclerosis, medial calcification, and microangiopathy, are
prevalent in patients with diabetes mellitus and are considered as the principal causes of
death and disability in these individuals. Atherosclerosis occurs earlier in patients with
diabetes, frequently with greater severity and more diffuse distribution. Patients with
diabetes have an increased prevalence of coronary artery disease, cerebrovascular disease,
peripheral arterial disease, and, as a result, more morbimortality due to acute myocardial
infarct. Microvascular disease also importantly contributes to morbidity. Diabetes and
metabolic syndrome is associated with vascular function abnormalities and the ensuing
morphologic changes associated with vascular remodeling and atherosclerosis. This
chapter will review current knowledge regarding the effect of metabolic syndrome on
vascular morphology and function.