Organosulfur compounds and cardiovascular disease

MARCELA VÁZQUEZ; ROBERTO MIATELLO

MOLECULAR ASPECTS OF MEDICINE

ELSEVIER SCIENCE BV

Lugar: Oxford, Elmsford, N. Y; Año: 2010 vol. 31 p. 540 - 545

0098-2997

Epidemiological studies have shown an inverse relationship between consumption of fruits and vegetables and the risk of cardiovascular disease. Phytochemicals are non-nutritional chemical compounds found in small quantities in fruits and vegetables with known health benefits. Among them, organosulfides are present mainly in garlic and onion characterized by their antioxidant and anti-inflammatory properties, and isothiocyanates in cruciferous vegetables have anticarcinogenic effects in experimental models. In this review, we are focusing on the main biological studies regarding the beneficial effect of organosulfur compounds on their protection against cardiovascular disease.