INVESTIGADORES
CESANI ROSSI Maria Florencia
artículos
Título:
Effect of intergenerational chronic undernutrition on ponderal, and linear growth
Autor/es:
CESANI MF; OYHENART EE; PUCCIARELLI ME
Revista:
ISRN Nutrition
Editorial:
Hindawi publishing corporation
Referencias:
Año: 2014 vol. 2014 p. 1 - 7
ISSN:
2314-4068
Resumen:
The aim of this paper was to analyze if intergenerational undernutrition causes growth retardation in weight and body length in two generations of rats, and if so, to assess whether the delay is cumulative. Male and female rats were assigned to one of the following groups: 1) Control: they were fed ad libitum and constituted the Parental generation (P), and 2) Undernourished generations (F1 and F2): they were fed on 75% of the control diet. Animals were weighted and X-rayed every ten days from 20 to 100 days old in order to measure total body length. Also, body mass index was calculated. Data were processed by ANOVA and LSD post hoc tests. Impairment in weight, body length and body mass index was found in both generations, nevertheless growth retardation was greater in F2, indicating a cumulative effect of nutritional stress. Sex differences were found, since the cumulative effect of generational undernutrition was greater and earlier in males than in females. It is concluded that: when the undernutrition acts with constant intensity during several generations, the growth retardation is cumulative, indicating a negative secular trend.