Exposure to a commercial glyphosate formulation (Roundup®) alters the normal gill and liver histology and affects the male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes).

HUED, A. C.; OBERHOFER, S. S.; BISTONI, M. A.

ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

SPRINGER

Año: 2011

0090-4341

Roundup® is the most popular commercial glyphosate formulation applied in cultivation of genetically modified glyphosate-resistant crops. The aim of this study was to evaluate the histological lesions of the Neotropical native fish, Jenynsia multidentata, in response to acute and subchronic exposure to Roundup and determine if the subchronic exposure to the herbicide cause changes in male sexual activity of individuals exposed to a sublethal concentration (0.5 mg/l) for 7 and 28 days of exposure. The estimated 96-h LC50 was 19.02 mg/l for both male and female individuals. The gill and liver histological lesions were evaluated through histopathological indices allowing the quantification of the histological damages in individuals exposed to different concentrations of the herbicide. Roundup induced different histological alterations in a concentration dependent manner. In subchronic exposure tests, Roundup also altered the normal histology of the studied organs and caused a significant decrease in the number of copulations and mating success in males exposed to the herbicide. It is expected that in natural environments contaminated with Roundup both general health condition and the reproductive success of J. multidenatata could be seriously affected.