INVESTIGADORES
GONZALEZ Marina Cecilia
congresos y reuniones científicas
Título:
GPAT3 AND GPAT4 DIRECT TRIACYLGLYCEROL SYNTHESIS DURING MACROPHAGE TO FOAM CELL TRANSITION AND THEIR DOWN-REGULATION ALTERS CYTOKINE RELEASE.
Autor/es:
QUIROGA YOSELY; PELLÓN MAISON, M.; GONZALEZ MARINA CECILIA; COLEMAN R; GONZALEZ BARÓ, MARÍA DEL ROSARIO
Reunión:
Congreso; FASEB- Federation of American Societies for Experimental Biology; 2018
Resumen:
De novo TAG synthesis is stimulated during macrophage to foam cell transition and contribute to lipid droplet incrase. GPAT3/4 contribute to lipid droplet, TAG and PL increase during macrophage to foam cell transition and are required to stimulate de novo TAG synthesis.GPAT4 could be implicated in pro-inflammatory cytokine release regulation.
