INVESTIGADORES
SALA Adriana Andrea
congresos y reuniones científicas
Título:
RELEVANT GENETIC CONTRIBUTION OF AMERINDIAN TO THE EXTANT POPULATION OF ARGENTINA
Autor/es:
DANIEL CORACH, MIGUEL MARINO AND ANDREA SALA
Lugar:
Grapevin, Texas USA
Reunión:
Simposio; 16th Intermnational Symposium on Human Identification; 2005
Institución organizadora:
Promega Corp,
Resumen:
The extant
population of Argentina claims to be the most European country of Latin
America. The statement has been held for over one century, and started when the
Campaign Against the
Dessert took place in 1870. This military mission was directed against the
aboriginal communities
in order to obtain their possessions. No scientific approach was available,
till recent, for checking
the supposed to be pure European ancestries. Uniparentally inherited genetic
markers, such as
mitochondrial DNA (mtDNA) and Single Nucleotide Polymorphisms (SNP) located in
the non
recombinant regions of the Y chromosome may clarify the strict European
ancestry of the
nowadays population of Argentina. A set of 322 unrelated males were chosen to
evaluate if
Amerindian markers such as the mitochondrial haplogroups A, B, C and D, as well
as the C to T
transition in locus DYS199 of the Y chromosome were present. Its detection in
the tested
individuals might suggest an ancestral contribution of Amerindian lineages.
Hiper Variable Region
(HVR) I and II were sequenced by Big Dye termination approach and the 9bp
ins/del in Region V was detected in automated platforms (ABI, 310 and
3100Avant). DYS199 C to T transition
detection was carried out by primer specific PCR. Over 65% of the individuals
tested carried
either mtDNA or Y Amerindian markers, 10% both, 20% were of Amerindian
patrilineage and less than 35% denoted non Amerindian contribution in the
uniparentally inherited markers. By this simple approach a different
contribution can be suggested within the most European country of Latin
America.