Penta-, nona- and decaplex Y-STR typing systems:

A. SALA A, M. HEDMAN B, M. MARINO A, A. SAJANTILA B,

INTERNATIONAL CONGRESS SERIES

ELSEVIER

Lugar: Amsterdam; Año: 2003 vol. 1239 p. 357 - 361

0531-5131

The analysis of Y chromosome-specific short tandem repeat (Y-STR) haplotypes allows patrilineage tracking and complements the highly robust autosomal STR systems used in forensic and kinship identification. Since 1994, in our lab, the use of the Y-STR Y27H39 (DYS19) was implemented. Later on, increasing availability of Y-STRs has broadened the patrilineage tracking potential. A complete nonaplex Y-STR set, including DYS385, 389 I and II, 390, 391, 392, 393 and DYS19, was investigated in 1995, provided information for the Charite Reference Database from Argentina and supported forensic casework investigations. For forensic purposes, we selected a pentaplex including: DYS19, DYS390, DYS391, DYS392 and DYS393. More recently, a decaplex, including DYS435, 436, 437, 438, 439, A7.1, H4, DYS19, DYS391 and DYS392, became available. In order to evaluate the penta-, nona- and decaplex Y-STR systems, unrelated Argentine males were analyzed (500, 100 and 104, respectively) by using an automated platform (ABI 310). For rapid forensic investigations, in which autosomal STR analysis is required, the pentaplex might be considered; if more informative data is required, nonaplex should be selected, especially due to worldwide internet supported Y-STR reference databases. It is suggested that part of the decaplex YSTR markers should be included in the Charite Database in order to stimulate the systems use.